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Director

INSTITUTE OF HOME ECONOMICS
UNIVERSITY OF DELHI

Name Prof. (Dr) Radhika Bakhshi
Designation Director
E-Mail principal@ihe.du.ac.in
PhotoGraph
Educational Qualifications:
  • ● MSc (Biochemistry), University of Delhi.
  • ● PhD (Biochemistry), AIIMS, New Delhi.
    		•
    Post-Doctoral and Teaching Experience:
  • 1. Wayne State University, Detroit, USA, Post-Doctoral Fellow: 3 yrs
  • 2. Sri Venkateswara College, University of Delhi, Lecturer, Department. of Biochemistry: 3 yrs
  • 3. Shaheed Rajguru College of Applied Sciences for Women, University of Delhi, Department of Biomedical Sciences: 18 yrs
    		•
    Awards Received :
  • 1. ‘Best Teacher’s Award’, by the Department of Higher Education, Govt. of NCT, Delhi in 2011.
  • 2. JRF and SRF from Council of Scientific and Industrial Research (CSIR).
  • 3. Qualified UGC-NET.
    		•
    Research Interest: Cancer Biology

    ORCID No: 0000-0002-1516-1339
    Research Project :
    Title

    Mutational analysis of PPARα, ABCC8, KCNJ11 & CALPN10 genes in Type 2 diabetes patients in India.

    Unraveling the Genetic Basis of Acute Myeloid Leukaemia (AML)

    Funding Agency

    University of Delhi – Innovation Project Scheme

    University of Delhi – Innovation Project Scheme

    Duration of the project

    1.5 Years

    01 Years

    Book Chapters Published/E-Content :
  • 1. 2023, Biomarkers for Low-Dose Ionizing Radiation-Induced Cancer Risk: An Overview, in the Book titled “Molecular Biomarkers in Cancer” : Techniques, Discoveries and Translational Applications, edited by Ranbir Chander Sobti, Haruhiko Sugimura and Awtar Krishan Ganju. ISBN(10) 1-4438-5758-0, ISBN (13): 978-1-4438-5758-1
  • 2. 2016-17- 3 Modules in ePG Pathshala (A UGC-MHRD initiative) for: Course – Biophysics, Paper-Thermodynamics of Living Systems and Bioenergetics.
  • 3. 2004, Recombinant DNA Technology, in the Book titled “Essentials of Biotechnology for Students”. ISBN 81-88-867-18-7
    • Research Publications Since 2010 :
  • 1. Sharawat SK, Bakhshi R,Vishnubhatla S, Bakhshi S. Mitochondrial D-loop variations in Paediatric acute myeloid leukaemia: a potential prognostic marker. Br J Haematol. 2010 May;149(3):391-8.
  • 2. Sharawat SK, Bakhshi R,Vishnubhatla S, Gupta R, Bakhshi S. BAX/BCL2 RMFI ratio predicts better induction response in Pediatric patients with acute myeloid leukemia. Pediatr Blood Cancer. 2013 Aug;60(8):E63-66.
  • 3. Sharawat SK, Gupta R, Raina V, Kumar L, Sharma A, Iqbal S, Bakhshi R, Vishnubhatla S, Bakhshi S. Increased coexpression of c-KIT and FLT3 receptors on myeloblasts: independent predictor of poor outcome in Pediatric acute myeloid leukemia. Cytometry B Clin Cytom. 2013 Nov-Dec;84(6):390-7.
  • 4. Sharawat SK, Bakhshi R, Vishnubhatla S, Gupta R, Bakhshi S. FLT3-ITD mutation in relation to FLT3 expression in Pediatric AML: a prospective study from India. Pediatric Hematol Oncol. 2014 Mar;31(2):131-7.
  • 5. Sharawat SK, Raina V, Kumar L, Sharma A, Bakhshi R, Vishnubhatla S, Gupta R, Bakhshi S. Quantitative assessment of BAX transcript and flow cytometric expression in acute myeloid leukemia: a prospective study. Hematology. 2014 Oct;19(7):404-11.
  • 6. Sharawat SK, Vishnubhatla S, Bakhshi R, Raina V, Kumar L, Sharma A, Bakhshi S. Relative receptor tyrosine kinases and anti-apoptotic transcripts hold potential for predicting inferior outcome in adult acute myeloid leukemia: a prospective pilot study. Clin Lymphoma Myeloma Leuk. 2014 Dec;14(6):501-508.
  • 7. Sharawat SK, Bakhshi R,Vishnubhatla S, Bakhshi S. High receptor tyrosine kinase (FLT3, KIT) transcript versus anti-apoptotic (BCL2) transcript ratio independently predicts inferior outcome in pediatric acute myeloid leukemia. Blood Cells Mol Dis. 2015 Jan;54(1):56-64.
  • 8. Sharawat SK, Raina V, Kumar L, Sharma A, Bakhshi R,Vishnubhatla S, Gupta R, Bakhshi S. High fms-like tyrosine kinase-3 (FLT3) receptor surface expression predicts poor outcome in FLT3 internal tandem duplication (ITD) negative patients in adult acute myeloid leukaemia : A prospective pilot study from India. Indian J Med Res. 2016 May;143(Supplement):S11-S16.
  • 9. Tyagi A, Pramanik R, Vishnubhatla S, Ali S, Bakhshi R, Chopra A, Singh A, Bakhshi S. Pattern of mitochondrial D-loop variations and their relation with mitochondrial encoded genes in pediatric acute myeloid leukemia. Mutat Res. 2018 Jul;810:13-18.
  • 10. Tyagi A, Pramanik R, Vishnubhatla S, Bakhshi R, Bakhshi S. Prognostic impact of mitochondrial DNA D-loop variations in pediatric acute myeloid leukemia.Oncotarget. 2019 Feb 12;10(13):1334-1343.
  • 11. Tyagi A, Pramanik R, Bakhshi R,Vishnubhatla S, Bakhshi S. Apoptosis: A biomarker of high- risk phenotype in pediatric acute myeloid leukemia? Int J Lab Hematol. 2019 Feb;41(1):141- 147.
  • 12. Tyagi A, Pramanik R, Bakhshi R, Singh A, Vishnubhatla S, Bakhshi S. Expression of mitochondrial genes predicts survival
  • 13. Tyagi A, Pramanik R, Bakhshi R,Vishnubhatla S, Bakhshi S. Genetic Landscape of Mitochondrial Regulatory Region in Pediatric Acute Myeloid Leukemia: Changes from Diagnosis to Relapse. J Pediatr Genet. 2019 Dec;8(4):193-197.
  • 14. Maan K, Tyagi R, Dutta A, Bakhshi R, Rana P. Comparative metabolic profiles of total and partial body radiation exposure in mice using an untargeted
  • 15. Chaudhary S, Ganguly S, Palanichamy JK, Singh A, Bakhshi R, Jain A, Chopra A, Bakhshi S. PGC1A driven enhanced mitochondrial DNA copy number predicts outcome in pediatric acute myeloid leukemia. Mitochondrion. 2021 May;58:246-254.
  • 16. Chaudhary S, Ganguly S, Singh A, Palanichamy JK, Chopra A, Bakhshi R,Bakhshi S. Mitochondrial complex II and V activity is enhanced in pediatric acute myeloid leukemia. Am J Blood Res. 2021 Oct 15;11(5):534-543.
  • 17. Maan K, Baghel R, Bakhshi R, Dhariwal S, Tyagi R, Rana P. An integrative chemometric approach and correlative metabolite networking of LC-MS and NMR based urine metabolomics for radiation signatures. Mol Omics. 2022 Mar 28;18(3):214-225.
  • 18. Chaudhary S, Ganguly S, Singh A, Palanichamy JK, Bakhshi R, Chopra A, Bakhshi S. Mitochondrial biogenesis gene POLG correlates with outcome in pediatric acute myeloid leukemia. Leuk Lymphoma. 2022 Apr;63(4):1005-1008.
  • 19. Kumari K, Singh KS, Singh K, Bakhshi R, Singh LR. TMAO to the rescue of pathogenic protein variants. Biochim Biophys Acta Gen Subj. 2022 Nov;1866(11):130214.
  • 20. Chaudhary S, Ganguly S, Palanichamy JK, Singh A, Pradhan D, Bakhshi R, Chopra A, Bakhshi S. Mitochondrial gene expression signature predicts prognosis of pediatric acute myeloid leukemia patients. Front Oncol. 2023 Feb 9;13:1109518
    • Association with Professional Societies
    Member of Society of Biological Chemists (India)